Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution01:25

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion01:20

Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

Drug metabolism, a critical process in the liver, involves two primary phases: Phase I reactions and Phase II conjugation. Obesity introduces significant alterations in this metabolic process, primarily due to fatty infiltration of the liver, leading to conditions such as nonalcoholic fatty liver disease (NAFLD). This condition can modify the activities of both Phase I and II enzymes, impacting how drugs are metabolized in obese patients.Phase I metabolism sees variable effects across...
Stress Prevention and Stress Management Techniques IV01:26

Stress Prevention and Stress Management Techniques IV

Stress often leads to unhealthy habits like smoking, excessive drinking, and overeating, which offer short-term relief but ultimately increase long-term health risks. These behaviors create a cycle that temporarily lowers stress levels but can result in severe long-term health consequences. Breaking these habits is essential to reduce the risk of chronic diseases and improve overall well-being. Three primary changes that support better health include quitting smoking, reducing alcohol intake,...
Type II Diabetes I: Introduction01:26

Type II Diabetes I: Introduction

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance, in which target tissues such as the liver, muscle, and adipose tissue respond poorly to insulin. It is also associated with inadequate compensatory insulin secretion, where pancreatic β-cells fail to produce sufficient insulin. Together, these abnormalities lead to persistent hyperglycemia.EtiologyT2DM develops through a complex interaction of genetic predisposition and environmental or...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Foods to Prevent Cardiometabolic Disease: Moving from "Saturated Fat" to "Whole Foods".

Current developments in nutrition·2026
Same author

The Effect of 4:3 Intermittent Fasting on Weight Loss at 12 Months.

Annals of internal medicine·2026
Same author

Weight loss associated with semaglutide use is linked to improved reproductive measures in polyendocrine metabolic ovarian syndrome: a proof-of-concept analysis.

Fertility and sterility·2026
Same author

The Use of Herbs and Spices to Improve Food Liking and Diet Quality.

Nutrition reviews·2026
Same author

Response to caution in interpreting the role of physical activity in weight loss maintenance among people with physical disabilities.

Disability and health journal·2026
Same author

A Pilot and Feasibility Study of Combined Oral Contraceptive Pills and Metabolic Outcomes in Premenopausal Women with Overweight or Obesity.

Women·2026
Same journal

Pneumonia Reimagined: Host, Microbe, and the Shifting Landscape of Disease.

Clinics in chest medicine·2026
Same journal

Advocacy in Pneumonia.

Clinics in chest medicine·2026
Same journal

Vaccines Against Pneumonia: Current Updates.

Clinics in chest medicine·2026
Same journal

Non-antibiotic Treatments for Pneumonia: Host-Directed Therapies, Next-Steps and Future Directions.

Clinics in chest medicine·2026
Same journal

Customizing Antibiotic Treatment for Pneumonia: Can We Have a Single Unified Algorithm for All Types of Pneumonia?

Clinics in chest medicine·2026
Same journal

The Role of Complex Digital Interventions to Improve Pneumonia Care.

Clinics in chest medicine·2026
See all related articles

Related Experiment Video

Updated: Jun 20, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

The obesity epidemic.

Victoria A Catenacci1, James O Hill, Holly R Wyatt

  • 1Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of Colorado Denver, Denver, CO 80220, USA.

Clinics in Chest Medicine
|August 25, 2009
PubMed
Summary
This summary is machine-generated.

Obesity is a widespread epidemic in the US, affecting all demographics and increasing risks for chronic diseases. Urgent public health strategies are needed to control this complex and growing health crisis.

More Related Videos

Methods for Presenting Real-world Objects Under Controlled Laboratory Conditions
06:54

Methods for Presenting Real-world Objects Under Controlled Laboratory Conditions

Published on: June 21, 2019

A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats
06:28

A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats

Published on: April 28, 2023

Related Experiment Videos

Last Updated: Jun 20, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

Methods for Presenting Real-world Objects Under Controlled Laboratory Conditions
06:54

Methods for Presenting Real-world Objects Under Controlled Laboratory Conditions

Published on: June 21, 2019

A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats
06:28

A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats

Published on: April 28, 2023

Area of Science:

  • Public Health
  • Epidemiology
  • Chronic Disease Management

Background:

  • Obesity prevalence in the US has reached epidemic proportions, affecting 35.1% of adults.
  • The condition affects all population segments and is increasing, particularly in children.
  • Obesity is linked to increased risks of diabetes mellitus, cardiovascular disease, and nonalcoholic fatty liver disease, reducing quality of life.

Purpose of the Study:

  • To highlight the severity and widespread impact of the obesity epidemic in the United States.
  • To underscore the associated health risks and potential decrease in life expectancy.
  • To emphasize the complexity and challenges in addressing obesity as a public health issue.

Main Methods:

  • This abstract is based on observational data and epidemiological statistics regarding obesity prevalence.
  • Analysis of current trends and projected health outcomes associated with the obesity epidemic.
  • Review of the multifaceted nature of obesity as a public health challenge.

Main Results:

  • Obesity affects 35.1% of US adults and is increasing across all demographics, especially in children.
  • Significant correlation between obesity and increased risk for major chronic diseases.
  • Potential for a reduced life expectancy in the current generation if the epidemic is not controlled.

Conclusions:

  • The obesity epidemic poses a significant and growing threat to public health in the US.
  • Addressing obesity requires complex, multifaceted public health interventions.
  • The current trajectory suggests a critical need for immediate and sustained action to combat rising obesity rates.