Obesity and respiratory diseases in childhood
Elizabeth K Fiorino1, Lee J Brooks
1Division of Pulmonary Medicine and Sleep Center, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.
Insights
Childhood obesity is rising and linked to reduced lung function and increased risks for conditions like asthma and obstructive sleep apnea. These conditions can lead to severe health issues, including obesity-hypoventilation syndrome.
Area of Science:
- Pediatric Health
- Respiratory Medicine
- Metabolic Disorders
Background:
- Childhood obesity rates have significantly increased over the last 50 years.
- Obesity is associated with reduced lung volumes due to increased chest and abdominal loading.
- The relationship between childhood obesity and asthma severity requires further investigation.
Purpose of the Study:
- To explore the multifaceted health implications of childhood obesity.
- To examine the link between obesity and respiratory issues in children.
- To assess the impact of obesity on conditions such as asthma and obstructive sleep apnea.
Main Methods:
- Review of epidemiological data on childhood obesity prevalence.
- Analysis of physiological mechanisms linking obesity to lung function.
- Examination of clinical associations between obesity and pediatric respiratory conditions.
Main Results:
- Obesity is linked to decreased lung volumes in children.
- Childhood obesity is a risk factor for obstructive sleep apnea (OSA).
- Severe obesity and OSA can contribute to obesity-hypoventilation syndrome and increase surgical risks.
Conclusions:
- Childhood obesity poses significant risks to respiratory health.
- Obesity is associated with increased severity and persistence of conditions like OSA.
- Addressing childhood obesity is crucial for preventing related respiratory complications.
Abstract:
The prevalence of childhood obesity has more than tripled over the past five decades. Obesity results in low lung volumes, likely through increased loading of the chest wall and abdomen. The prevalence of asthma in children has paralleled the rise in obesity; obesity may increase the severity of asthma, but a direct link has been difficult to establish. Obesity is a risk factor for obstructive sleep apnea (OSA) in children as well as adults. Obese children may be at increased risk for persistent OSA following adenotonsillectomy treatment for OSA. Severe obesity and OSA may lead to the obesity-hypoventilation syndrome, with hypoxia, hypercapnia, and reduced ventilatory drive. Obesity can increase a child's risk for complications of anesthesia and recovery from surgery.
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