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Updated: Jun 20, 2026

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
Published on: December 14, 2020
Association of a globus sensation with esophageal diseases
Hiromi Nagano1, Kousuke Yoshifuku, Yuichi Kurono
1Department of Internal Medicine, Kashima Hospital, 1530-6 Kashima, Satsumasenndai, Kagoshima, Japan. hiromi.n.6_9@k3.dion.ne.jp
Objective:
The aim of the study was to clarify the relationship between a globus sensation and esophageal diseases using upper gastrointestinal endoscopy.
Methods:
The study population consisted of 52 consecutive patients (33 men, 19 women, age 46-94 years old) with a globus sensation without laryngeal and hypopharyngeal findings who were referred to the Department of Otolaryngology at Ooshima Prefecture Hospital. The subjects were examined by upper gastrointestinal endoscopy.
Results:
Nineteen patients (36.5%) had esophageal disorder, including 10 cases of reflux esophagitis, 5 of esophageal candidiasis, 3 of esophageal cancer. and 1 of herpes and reflux esophagitis. Neither age nor duration of symptoms differed significantly between patients without an esophageal disorder and those with reflux esophagitis or esophageal candidiasis.
Conclusions:
The results suggest that examination for esophageal diseases is important in patients with a globus sensation without laryngeal and hypopharyngeal findings.
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