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Related Experiment Video

Updated: Jun 20, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

Published on: June 11, 2019

Vasoactive mediastinal mass in an infant.

Ann G Bailey¹, Genevieve Mounce

¹Department of Anesthesiology, University of North Carolina, Chapel Hill, NC 27599-7010, USA. abailey@aims.unc.edu

Journal of Clinical Anesthesia

|August 25, 2009

Summary

A rare case of infant neuroblastoma presented as an anterior mediastinal mass, causing hemodynamic instability during surgery. This highlights the importance of considering neuroblastoma in pediatric anterior mediastinal masses.

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Last Updated: Jun 20, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques

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Published on: June 11, 2019

A Modified Sonographic Algorithm for Image Acquisition in Life-Threatening Emergencies in the Critically Ill Newborn

A Modified Sonographic Algorithm for Image Acquisition in Life-Threatening Emergencies in the Critically Ill Newborn

Published on: April 7, 2023

Area of Science:

Pediatric Oncology
Thoracic Surgery
Medical Diagnostics

Background:

Anterior mediastinal masses in infants are rare and can present diagnostic challenges.
Neuroblastoma is a common pediatric malignancy, typically originating in the adrenal glands or sympathetic chain.

Observation:

A 6-week-old infant presented with a large anterior mediastinal mass extending to the neck.
During surgical exploration, the infant experienced severe hemodynamic instability, suggesting a vasoactive tumor.

Findings:

The mass was identified as a neuroblastoma originating in the posterior mediastinum.
The tumor's significant mass effect was located anteriorly and extended into the neck, mimicking a primary anterior mediastinal tumor.

Implications:

This case underscores the need for a broad differential diagnosis for anterior mediastinal masses in neonates and infants.
Early recognition of potential vasoactive properties of mediastinal tumors is crucial for surgical planning and patient management.
Neuroblastoma should be considered in the differential diagnosis of pediatric anterior mediastinal masses, even with atypical presentation.