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ErythRED, a hESC line enabling identification of erythroid cells

Tanya Hatzistavrou1, Suzanne J Micallef, Elizabeth S Ng

  • 1Monash Immunology and Stem Cell Laboratories, Monash University, Clayton, Victoria, Australia.

Nature Methods
|August 25, 2009
PubMed

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Red blood cells  (RBCs) transport oxygen to all body tissues. These cells survive only for 120 days and then need to be replenished. Erythropoiesis is the process of RBC production. In healthy individuals, erythropoiesis ensures all tissues are amply supplied with oxygen. In addition, blood loss due to injury leads to a drop in the physiological oxygen level that will cause erythropoiesis. Any defect in erythropoiesis leads to several physiological disorders, including thalassemia, anemia, and...