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Post-traumatic Stress Disorder

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Related Experiment Video

Updated: Jun 20, 2026

Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity

Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity

Published on: July 1, 2014

Longitudinal effects of PTSD on memory functioning.

Kristin W Samuelson¹, Thomas C Neylan, Maryanne Lenoci

¹Mental Health Service, San Francisco Veteran's Affairs Medical Center, San Francisco, CA 94133, USA. ksamuelson@alliant.edu

Journal of the International Neuropsychological Society : JINS

|August 26, 2009

Summary

This summary is machine-generated.

This study examined longitudinal memory changes in Vietnam veterans with posttraumatic stress disorder (PTSD). Veterans with PTSD showed a very slight decline in facial recognition memory over time compared to those without PTSD.

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Area of Science:

Neuroscience
Psychology
Gerontology

Background:

Posttraumatic stress disorder (PTSD) is linked to memory deficits.
Longitudinal memory changes in aging veterans with PTSD remain understudied.
Previous research suggests PTSD and aging interact to affect memory in older trauma survivors.

Purpose of the Study:

To investigate the longitudinal trajectory of memory functioning in Vietnam War veterans with and without PTSD.
To assess changes in visual memory, verbal memory, and working memory over time.
To determine if PTSD influences the rate of cognitive decline in aging veterans.

Main Methods:

Neuropsychological tests assessing visual and verbal memory, and working memory were administered.
Participants included 25 veterans with PTSD and 22 veterans without PTSD, aged 41-63 at baseline.
Assessments were conducted at two time points, with a mean interval of 34 months.

Main Results:

The PTSD group did not exhibit significant changes in PTSD symptom severity over the study period.
Veterans with PTSD showed a statistically significant, yet extremely subtle, decline in delayed facial recognition compared to controls.
No significant differences in longitudinal changes were observed for other memory measures.

Conclusions:

Chronic PTSD in aging Vietnam veterans is associated with a minimal decline in facial recognition memory.
Longitudinal memory functioning in this population appears largely stable, with subtle effects observed.
Further research is needed to understand the long-term cognitive impact of PTSD in aging veterans.