Dynamic compression of the left main coronary artery by the left atrium

Robin A Ducas1, Davinder S Jassal, Iain D C Kirkpatrick

  • 1Department of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada. jducas@sbgh.mb.ca

Insights

Severe mitral regurgitation caused dynamic compression of the left main coronary artery due to enlarged left atrium. This led to heart failure symptoms and angina in a 67-year-old woman.

Area of Science:

  • Cardiology
  • Cardiac Imaging
  • Vascular Physiology

Background:

  • A 67-year-old woman presented with worsening heart failure and angina.
  • Her medical history included severe mitral valve regurgitation.

Observation:

  • Coronary angiography showed dynamic systolic flow limitation in the left main (LM) coronary artery without atherosclerotic disease.
  • Intravascular ultrasound revealed systolic LM coronary artery distortion and cross-sectional area reduction.
  • Cardiac CT demonstrated left atrial enlargement compressing the LM coronary artery.

Findings:

  • The patient was diagnosed with dynamic compression of the LM coronary artery.
  • This compression was secondary to systolic left atrial enlargement caused by mitral regurgitation.

Implications:

  • This case highlights a rare cause of coronary artery compression.
  • It underscores the importance of considering dynamic mechanical factors in coronary artery disease diagnosis.
  • Accurate diagnosis requires integrated interpretation of angiography, intravascular ultrasound, and cardiac CT.

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