Glycemic control for postoperative pediatric cardiac patients

Catherine M Preissig1, Mark R Rigby, Kevin O Maher

  • 1Department of Pediatrics, Division of Critical Care Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA. catherine.preissig@choa.org

Pediatric Cardiology
|August 26, 2009
PubMed

Insights

Hyperglycemia is common in pediatric cardiac surgery patients, impacting outcomes. A specialized protocol effectively managed blood glucose levels without increasing hypoglycemia risks.

Area of Science:

  • Pediatric Critical Care Medicine
  • Endocrinology
  • Cardiovascular Surgery

Background:

  • Hyperglycemia is a frequent complication in pediatric patients post-cardiac surgery.
  • The clinical significance and effective management of hyperglycemia in this vulnerable population remain critical areas of investigation.

Purpose of the Study:

  • To determine the prevalence of hyperglycemia in pediatric postoperative cardiac patients.
  • To assess the impact of hyperglycemia on patient outcomes.
  • To evaluate the efficacy and safety of a pediatric-specific glycemic control protocol for managing hyperglycemia.

Main Methods:

  • Retrospective chart review of 100 pediatric postoperative cardiac intensive care unit (ICU) patients.
  • Defined hyperglycemia as blood glucose (BG) > 7.7 mmol/l (140 mg/dl).
  • Evaluated outcomes and analyzed BG control in 20 patients managed with a pediatric-specific insulin protocol.

Main Results:

  • Hyperglycemia prevalence was 84% among studied patients.
  • Hyperglycemic patients exhibited higher inotrope scores, prolonged hospital stays, increased mechanical ventilation days, and elevated mortality rates.
  • The pediatric glycemic control protocol achieved 62% of BG values within the target range with <4% of values below 3.3 mmol/l (60 mg/dl), and no BG < 2.2 mmol/l (40 mg/dl).

Conclusions:

  • Severe hyperglycemia is highly prevalent in pediatric postoperative cardiac patients and is associated with increased morbidity and mortality.
  • A pediatric-specific glycemic control protocol can effectively manage hyperglycemia in these patients, with a low risk of hypoglycemia.

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