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Updated: Jun 20, 2026
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Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
Published on: August 15, 2025
Temporal fossa hemangiopericytoma: a case series
Marc A Heiser1, James S Waldron, Tarik Tihan
1Department of Otolaryngology-Head and Neck Surgery, University of California at San Francisco, San Francisco, California 94143-0342, USA. marc.heiser@ucsf.edu
Summary
Management of temporal fossa hemangiopericytomas (HPCs) is challenging due to late presentation and surgical difficulty. A multidisciplinary approach is key for improving outcomes and curability of these rare tumors.
Area of Science:
- Neurosurgery
- Oncology
- Pathology
Background:
- Temporal fossa hemangiopericytomas (HPCs) are rare intracranial tumors.
- Clinical presentation is often delayed, complicating diagnosis and treatment.
Observation:
- A retrospective review of five temporal fossa HPC cases treated between 1995 and 2008.
- Patients presented with varied symptoms, most commonly headache.
- Tumor excision was gross total in two patients and subtotal in three due to intraoperative blood loss or adherence to vital structures.
Findings:
- Histologically, tumors showed tightly packed cells with a vascular background highlighted by CD34 staining.
- Outcomes included two patients alive with no evidence of disease, two alive with disease, and one deceased due to the disease.
Implications:
- Complete tumor resection is often limited by the proximity of vital cranial base and intracranial structures.
- A multidisciplinary approach involving neurosurgery and neurotology is crucial for optimizing tumor removal and patient survival.
- Effective management strategies are needed to improve symptom-free survival and curability for these challenging lesions.
