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Updated: Jun 20, 2026

Acute Mouse Brain Slicing to Investigate Spontaneous Hippocampal Network Activity
Published on: August 28, 2020
Imagining the possibilities: ripples, routes, and reactivation
1Zanvyl Krieger Mind/Brain Institute and Department of Neuroscience, Johns Hopkins University, Baltimore, MD 21218, USA. jknierim@jhu.edu
Abstract:
Hippocampal place cells fire selectively when a rat occupies a particular location. Under certain conditions, the cells briefly represent trajectories along locations away from the rat's current location. New results lend important insight into this phenomenon and demonstrate spatiotemporally coherent, cognitive representations that are independent of current sensory input.
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