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Published on: June 26, 2020
A hepatitis E outbreak caused by a temporary interruption in a municipal water treatment system, Baripada, Orissa,
Susanta K Swain1, Prameela Baral, Yvan J Hutin
1Field Epidemiology Training Programme, Master of Applied Epidemiology, National Institute of Epidemiology, Indian Council of Medical Research, Chennai, Tamil Nadu, India.
Abstract:
In January 2004, we investigated a cluster of acute hepatitis in Baripada, Orissa, India. Between January and March 2004, 538 cases (definition: fever with loss of appetite and jaundice) were reported (attack rate: 263 per 100 000, 5 deaths, case fatality rate: 0.93%). Forty-seven of 48 sera were positive for IgM antibodies to hepatitis E virus. Cases peaked in February 2004 and decreased rapidly, suggesting a common source outbreak. Five neighbourhoods supplied by a common water supply were most affected. Ninety-one percent of the 538 cases and 30% of 538 unaffected controls reported drinking water from one source (odds ratio 31, 95% CI 27-48). The neighbourhood's water was pumped directly from a river and had not been treated during a 10-day period in early January (1 month before the peak of the outbreak) because of a strike at the treatment plant. This large hepatitis E outbreak was associated with drinking untreated raw river water. Measures must be in place to check the quality of municipal water and to ensure essential services in case of strikes.
Insights
A large hepatitis E outbreak in India was caused by drinking untreated river water. Public health measures are needed to ensure safe water supplies, especially during service disruptions.
Area of Science:
- Public Health
- Epidemiology
- Infectious Diseases
Background:
- A significant outbreak of acute hepatitis occurred in Baripada, Orissa, India, in early 2004.
- The outbreak involved 538 reported cases with a notable attack rate and a small number of fatalities.
Purpose of the Study:
- To investigate the cause of the acute hepatitis cluster in Baripada.
- To identify the source of infection and risk factors associated with the outbreak.
Main Methods:
- Case definition: fever with loss of appetite and jaundice.
- Serological testing for IgM antibodies to hepatitis E virus.
- Case-control study comparing water sources of affected and unaffected individuals.
Main Results:
- 47 out of 48 sera tested positive for hepatitis E virus IgM antibodies.
- A strong association was found between drinking water from a specific untreated river source and illness (OR 31).
- The outbreak coincided with a 10-day period of untreated water supply due to a strike at the treatment plant.
Conclusions:
- The hepatitis E outbreak was strongly linked to the consumption of untreated raw river water.
- Ensuring the quality of municipal water supplies and maintaining essential services during strikes are critical public health interventions.
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