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Related Concept Videos

The Oral Microbiota01:27

The Oral Microbiota

The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...
Development of the Oral Microbiota01:28

Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
Microbiota of the Respiratory Tract01:29

Microbiota of the Respiratory Tract

The human respiratory tract, comprising the upper and lower segments, serves as a critical interface with the external environment. The upper respiratory tract (URT)—including the nostrils, sinuses, pharynx, and oropharynx—is heavily colonized by microbes, while the lower respiratory tract (LRT), composed of the larynx, trachea, bronchi, and lungs, was long thought to be sterile. However, recent molecular studies have revealed that the lungs are not devoid of microbes but act more like...
The Skin Microbiota01:27

The Skin Microbiota

The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...
Microbiome of the Eye01:22

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The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
Microbiota of the Urogenital Tract01:28

Microbiota of the Urogenital Tract

The human urogenital system, once thought to be sterile in healthy individuals, is now recognized as a complex microbial habitat. Advancements in molecular sequencing techniques have revealed that even in healthy adults, the kidneys and bladder harbor microbial populations similar to those found in the distal urethra, albeit in much lower abundance. These resident microorganisms, while generally innocuous, can become opportunistic pathogens under conditions that alter the urogenital...

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Oral Biofilm Formation on Different Materials for Dental Implants
11:19

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Published on: June 24, 2018

Microflora associated with successful and failed orthodontic mini-implants.

Stephanie Apel1, Christian Apel, Camillo Morea

  • 1Department of Orthodontics, University of São Paulo, São Paulo, Brazil.

Clinical Oral Implants Research
|September 2, 2009
PubMed
Summary

Orthodontic mini-implants showed no specific aggressive bacteria linked to failure. Stable implants, however, showed higher presence of Actinomyces viscosus and Campylobacter gracilis.

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Area of Science:

  • Orthodontics
  • Microbiology
  • Biomaterials

Background:

  • Mini-implants are crucial for orthodontic anchorage.
  • Instability and loss of mini-implants can occur due to various factors, including bacterial colonization.
  • Understanding the microflora associated with mini-implant success or failure is important.

Purpose of the Study:

  • To screen the microflora associated with successful and failed orthodontic mini-implants.
  • To investigate the role of bacterial colonization in mini-implant stability.

Main Methods:

  • Analyzed 76 mini-implants from 25 patients undergoing orthodontic treatment.
  • Used real-time quantitative PCR and microarray-based identification for bacterial analysis.
  • Compared microflora of eight failed implants with four successful control implants.

Main Results:

  • The mini-implant failure rate was 10.5%.
  • No significant difference in total bacterial load or species composition was found between failed and successful implants.
  • Actinomyces viscosus and Campylobacter gracilis were more prevalent in stable implants than in failed ones.

Conclusions:

  • The peri-implant sulcus of failed orthodontic mini-implants did not exhibit a specific aggressive bacterial flora.
  • Specific bacterial species may play a role in maintaining mini-implant stability.