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Motivation and patch treatment for HIV+ smokers: a randomized controlled trial
Elizabeth E Lloyd-Richardson1, Cassandra A Stanton, George D Papandonatos
1Department of Psychiatry and Human Behavior, The Warren Alpert Medical School of Brown University, Centers for Behavioral and Preventive Medicine, The Miriam Hospital, Providence, RI, USA. erichardson@umassd.edu
Intensive motivational counseling did not improve smoking cessation rates for HIV+ individuals compared to standard care. Brief support and nicotine replacement therapy (NRT) may aid cessation in this population.
Area of Science:
- Public Health
- Clinical Medicine
- Addiction Research
Background:
- Smoking remains a significant health concern for individuals with HIV.
- Effective smoking cessation interventions are crucial for improving health outcomes in this population.
Purpose of the Study:
- To compare the efficacy of standard care (SC) plus nicotine replacement therapy (NRT) with motivationally enhanced (ME) treatment plus NRT for smoking cessation in HIV+ individuals.
Main Methods:
- A randomized controlled trial involving 444 HIV+ smokers from eight clinics in the northeastern United States.
- Participants received either SC (brief sessions, self-help materials, NRT) or ME (four counseling sessions, tailored materials, NRT).
- Biochemically verified 7-day abstinence rates were assessed at 2, 4, and 6 months.
Main Results:
- No significant differences in abstinence rates were observed between the ME and SC groups at any follow-up point.
- Higher motivation to quit, lower nicotine dependence, and Hispanic American ethnicity were associated with successful cessation.
- Each additional NRT contact was associated with a one-third increase in the odds of smoking abstinence.
Conclusions:
- Motivationally enhanced treatment did not demonstrate superior efficacy over standard care plus NRT for smoking cessation in HIV+ individuals.
- Brief interventions and encouragement of NRT use by healthcare providers may support smoking cessation efforts in this population.
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