Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Dementia l: Introduction01:22

Dementia l: Introduction

Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...
Dementia01:30

Dementia

Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual.
Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
Stroke: Introduction and Types01:29

Stroke: Introduction and Types

A stroke is an acute neurological event caused by the sudden disruption of cerebral blood flow, leading to rapid loss of neuronal function. Neurons depend on continuous oxygen and glucose supply, so even brief interruptions can cause irreversible injury within minutes. Strokes are classified into ischemic and hemorrhagic types.Ischemic StrokeIschemic strokes are most common and occur due to arterial occlusion, depriving brain tissue of oxygen and nutrients. This leads to energy failure, ionic...
Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
Ischemic Stroke l: Introduction01:15

Ischemic Stroke l: Introduction

Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Emerging Concepts in Vascular Dementia: A Review.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2021
Same author

An Uncommon Recurrence of Carcinoma Ex Pleomorphic Adenoma.

Ear, nose, & throat journal·2020
Same author

Focal epilepsy caused by single cerebral cavernous malformation (CCM) is associated with regional and global resting state functional connectivity (FC) disruption.

NeuroImage. Clinical·2019
Same author

Neurocognitive testing and cochlear implantation: insights into performance in older adults.

Clinical interventions in aging·2016
Same author

Traumatic Brain Injury and Behavior: A Practical Approach.

Neurologic clinics·2015
Same author

Toxic-metabolic, nutritional, and medicinal-induced disorders of cerebellum.

Neurologic clinics·2014
Same journal

Predictive ability of cardiac biomarkers for early risk stratification and 3-month functional outcomes after reperfusion therapy in acute ischemic stroke.

Neurological research·2026
Same journal

Luteolin reduces sciatic nerve damage and modulates TRPV1 and TRPM2 expression in diabetic rats.

Neurological research·2026
Same journal

Cholinergic regulation of memory retrieval: scopolamine reduces hippocampal neurotrophic and metabolic support.

Neurological research·2026
Same journal

Effect of intravenous thrombolysis on arterial and venous profiles in large-vessel occlusion stroke: a retrospective propensity score-matched study.

Neurological research·2026
Same journal

Association between post-treatment neuroimaging markers of cerebral small vessel disease and short-term efficacy of recombinant tissue plasminogen activator in acute stroke patients.

Neurological research·2026
Same journal

Association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and the characteristics of carotid artery plaques: a retrospective study and machine learning model construction.

Neurological research·2026
See all related articles

Related Experiment Video

Updated: Jun 20, 2026

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats
04:38

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

Published on: May 22, 2019

Stroke and dementia.

James B Pinkston1, Nadejda Alekseeva, Eduardo González Toledo

  • 1Department of Neurology, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USA. jpinks@lsuhsc.edu

Neurological Research
|September 3, 2009
PubMed
Summary
This summary is machine-generated.

Vascular dementia, often caused by stroke, leads to disability and cognitive decline. While distinct from Alzheimer's dementia, differentiating them is key for effective treatment planning and stroke prevention strategies.

More Related Videos

A Mouse Model for Vascular Cognitive Impairment and Dementia Based on Needle-guided Asymmetric Bilateral Common Carotid Artery Stenosis
05:12

A Mouse Model for Vascular Cognitive Impairment and Dementia Based on Needle-guided Asymmetric Bilateral Common Carotid Artery Stenosis

Published on: November 22, 2024

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients
07:42

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients

Published on: December 16, 2022

Related Experiment Videos

Last Updated: Jun 20, 2026

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats
04:38

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

Published on: May 22, 2019

A Mouse Model for Vascular Cognitive Impairment and Dementia Based on Needle-guided Asymmetric Bilateral Common Carotid Artery Stenosis
05:12

A Mouse Model for Vascular Cognitive Impairment and Dementia Based on Needle-guided Asymmetric Bilateral Common Carotid Artery Stenosis

Published on: November 22, 2024

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients
07:42

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients

Published on: December 16, 2022

Area of Science:

  • Neurology
  • Gerontology
  • Public Health

Background:

  • Vascular dementia is a significant cause of disability and cognitive impairment following stroke.
  • Stroke affects approximately 660,000 individuals annually in the USA, with a substantial portion developing dementia.
  • Emerging research highlights commonalities and distinctions between vascular dementia and Alzheimer's dementia.

Purpose of the Study:

  • To review the causes and risk factors of vascular dementia.
  • To compare and contrast vascular dementia with Alzheimer's dementia, including diagnostic approaches.
  • To discuss neuropsychological findings, stroke prevention, and potential treatments for cognitive decline in vascular dementia.

Main Methods:

  • A literature review of recent peer-reviewed publications on vascular dementia was conducted using PubMed.

Main Results:

  • Vascular dementia presents with variable causes and manifestations, often distinct from Alzheimer's dementia.
  • Neuropsychological impairment profiles can aid in differentiating vascular dementia from Alzheimer's dementia.
  • Stroke remains a leading cause of dementia, disability, and death.

Conclusions:

  • Vascular dementia contributes to dependence and disability, particularly among stroke survivors.
  • Improved understanding of vascular dementia is enhancing treatment planning.
  • Further research is crucial for developing effective treatments for vascular dementia and its associated cognitive decline.