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Updated: Jun 20, 2026

Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid
Published on: June 17, 2025
Pemphigus vulgaris presenting as an isolated crusted plaque of the cheek
Elhem Khelifa1, Rym Benmously, Talel Badri
1Dermatology Department, Habib Thameur Hospital, Tunisia. elhem_khelifa@yahoo.com
Abstract:
A healthy 45-year-old man presented with a three-month history of an isolated enlarging eroded plaque on the left cheek. Pemphigus vulgaris was diagnosed by biopsy and positive direct immunofluorescence. The patient was lost to follow up, but returned two months later with generalized cutaneous involvement without mucosal involvement. He responded rapidly to oral corticosteroid therapy.
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