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Screening for reactive metabolites using electro-optical arrays featuring human liver cytosol and microsomal enzyme
Linlin Zhao1, John B Schenkman, James F Rusling
1Department of Chemistry, University of Connecticut, 55 N. Eagleville Rd, Storrs, CT, USA.
Abstract:
We demonstrate for the first time the combination of human liver cytosol and microsomal enzyme sources into an electro-optical array to screen for reactive metabolites produced in multi-enzyme metabolic processes.
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