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Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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Updated: Jun 20, 2026

Rapid Homogeneous Detection of Biological Assays Using Magnetic Modulation Biosensing System

Rapid Homogeneous Detection of Biological Assays Using Magnetic Modulation Biosensing System

Published on: June 13, 2010

A compact surface decontamination system for surface-sensitive magnetic imaging.

M Konoto¹, H Akoh, Y Tokura

¹National Institute of Advanced Industrial Science and Technology, 1-1-1 Higashi, Tsukuba 305-8562, Japan. m.konoto@aist.go.jp

The Review of Scientific Instruments

|September 4, 2009

Summary

This study introduces a novel surface decontamination system using active oxygen for sensitive magnetic imaging tools. It effectively cleans fragile oxide surfaces without causing damage, enabling detailed magnetic domain analysis.

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Rapid Homogeneous Detection of Biological Assays Using Magnetic Modulation Biosensing System

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Published on: June 13, 2010

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Area of Science:

Materials Science
Surface Science
Microscopy

Background:

Surface contamination is a significant challenge in high-resolution magnetic imaging.
Conventional cleaning methods like physical etching can damage sensitive magnetic materials, particularly complex oxides.
Fragile magnetic surfaces require non-destructive cleaning techniques for accurate analysis.

Purpose of the Study:

To develop and present a novel surface decontamination system for magnetic imaging tools.
To enable the cleaning of surface-sensitive and fragile magnetic materials, such as complex oxides.
To facilitate the detection and visualization of magnetic domain structures on decontaminated surfaces.

Main Methods:

A compact vacuum chamber integrated into a microscope.
Chemical decomposition of adsorbed contaminants using active oxygen.
Application of the system to spin-polarized scanning electron microscopy (SP-SEM).

Main Results:

Successful decontamination of fragile complex oxide surfaces.
Detection of magnetic signals from cleaned oxide surfaces.
Visualization of magnetic domain images with sufficient contrast for detailed structural analysis.

Conclusions:

The active oxygen-based decontamination system is effective for surface-sensitive magnetic imaging tools.
This method is suitable for fragile magnetic oxide materials, avoiding structural damage.
The system enables high-contrast magnetic domain imaging and analysis of complex oxides.