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Current Management of Schizophrenia: Antipsychotic Monotherapy versus Combination Therapy
Elisa F Cascade1, Amir H Kalali, Peter F Buckley
1Ms. Cascade is Vice President, Quintiles Inc./iGuard, Falls Church, Virginia.
Abstract:
We investigated the current practice for treatment of schizophrenia. According to our data, 47 percent of patients with schizophrenia are treated with only antipsychotic medication. An additional 43 percent of patients receive one additional class to supplement their antipsychotic medication, and 10 percent of patients are prescribed two or more classes of drugs in addition to an antipsychotic medication. The most common classes used to supplement antipsychotic medications in the management of schizophrenia include antidepressants (28%), mood stabilizers (18%), agents to treat extrapyramidal symptoms (7%), and sleep aids (5%).
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