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A Within-Subject Experimental Design using an Object Location Task in Rats

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The Rotterdam Study: 2010 objectives and design update.

Albert Hofman¹, Monique M B Breteler, Cornelia M van Duijn

¹Department of Epidemiology, Erasmus Medical Center, PO Box 2040, 3000 CA Rotterdam. The Netherlands. a.hofman@erasmusmc.nl

European Journal of Epidemiology

|September 4, 2009

Summary

The Rotterdam Study is a long-term population study investigating multiple diseases in older adults. Its extensive research has yielded nearly 1,000 publications on cardiovascular, neurological, and other health conditions.

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Area of Science:

Epidemiology
Gerontology
Public Health

Background:

The Rotterdam Study, initiated in 1990, is a major prospective cohort study in the Netherlands.
It focuses on a wide range of age-related diseases, including cardiovascular, endocrine, hepatic, neurological, ophthalmic, psychiatric, and respiratory conditions.
The cohort includes a substantial number of participants aged 45 and over.

Purpose of the Study:

To investigate the etiology, incidence, and progression of various chronic diseases in an aging population.
To provide a comprehensive understanding of health and disease patterns in older adults.
To serve as a foundation for numerous research articles and reports, contributing significantly to scientific knowledge.

Main Methods:

Prospective cohort study design.
Longitudinal data collection from a large population sample.
Ongoing research with regular updates to objectives and methodologies.

Main Results:

The study has generated a vast body of research, with close to 1,000 publications.
Findings cover a broad spectrum of diseases affecting older individuals.
The research provides critical insights into disease risk factors and outcomes.

Conclusions:

The Rotterdam Study is a vital resource for understanding age-related diseases.
Its comprehensive data collection and extensive research output have significantly advanced medical knowledge.
The study continues to provide valuable insights into public health and aging.