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Updated: Jun 20, 2026

Whole Genome Sequencing of Candida glabrata for Detection of Markers of Antifungal Drug Resistance
Published on: December 28, 2017
Two closely related fluconazole-resistant Candida tropicalis clones circulating in Taiwan from 1999 to 2006
Shu-Ying Li1, Yun-Liang Yang, Yu-Hsin Lin
11 Mycotic Diseases Laboratory, Research and Diagnostic Center, Centers for Disease Control , Taipei, Taiwan .
Abstract:
Recently, we reported that diploid sequence type (DST) 140 was a predominant type of Candida tropicalis among isolates with fluconazole minimum inhibitory concentrations (MICs) >or=64 microg/ml collected in the Taiwan Surveillance of Antimicrobial Resistance of Yeasts (TSARY) in 1999. To determine if DST140 persists in Taiwan, we have used multilocus sequence typing to characterize the genetic profiles of 31 resistant isolates (MICs >or=64 microg/ml), together with 19 susceptible isolates (MICs
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