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Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

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Published on: June 7, 2015

Motion-induced dose artifacts in helical tomotherapy.

Bryan Kim¹, Jeff Chen, Tomas Kron

¹London Regional Cancer Program, London Health Sciences Centre, London, ON, Canada. bryan.kim@lhsc.on.ca

Physics in Medicine and Biology

|September 5, 2009

Summary

Tumor motion during helical tomotherapy causes dose artifacts like rounding and rippling. A new artifact, IMRT leaf opening asynchronization, was also identified, impacting treatment accuracy.

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Area of Science:

Medical Physics
Radiation Oncology
Image-Guided Therapy

Background:

Tumor motion poses challenges for precise radiation delivery in helical tomotherapy.
Dynamic changes in gantry, couch, and Multi-Leaf Collimator (MLC) complicate treatment accuracy.

Purpose of the Study:

Investigate motion-induced dose artifacts in helical tomotherapy.
Characterize dose rounding, dose rippling, and a novel IMRT leaf opening asynchronization effect.
Analyze artifact impact based on motion amplitude and period.

Main Methods:

Computer simulation modeling of helical tomotherapy.
Experimental verification of simulated dose distributions.
Analysis of dose profiles under varying motion conditions (amplitude, period).

Main Results:

Dose rounding increased penumbra up to 20.5 mm with 1.0-5.0 cm motion amplitude.
Dose rippling reached 25% magnitude at a 10s motion period.
IMRT leaf opening asynchronization caused dose variations from -29% to 7% within the planning target volume (PTV).

Conclusions:

Tumor motion significantly impacts helical tomotherapy dose delivery.
Identified and quantified three distinct motion-induced dose artifacts.
Findings are crucial for developing motion mitigation strategies in lung tomotherapy.