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Coumestan glycosides from the stem bark of Cylicodiscus gabunensis
Kazie Nchancho1, Jacques Kouam, Pierre Tane
1Department of Organic Chemistry, Faculty of Science, University of Yaoundi I, P.O. Box 812, Cameroon.
Natural Product Communications
|September 8, 2009
Abstract:
Two new coumestan glycosides, coumestoside C (1) and coumestoside D (2), were isolated from the stem bark of Cylicodiscus gabunensis Harms. Their structures were established by spectroscopic means and chemical transformations as 9-O-alpha-L-rhamnopyranosyl-3-hydroxy-4-(5'-hydroxy-3'-methylbut-2'E-enyl) coumestan (1) and 9-O-beta-D-galactopyranosyl-3-O- prenyl-4-hydroxycoumestan. Coumestoside C exhibited antimicrobial activity against Proteus vulgaris.
