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Genomics

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Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...

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Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts

Published on: July 25, 2020

Update on genomics in veterinary oncology.

Matthew Breen¹

¹Department of Molecular Biomedical Sciences, College of Veterinary Medicine, and Center for Comparative Medicine and Translational Research, North Carolina State University, Raleigh, NC 27606, USA. Matthew_Breen@ncsu.edu

Topics in Companion Animal Medicine

|September 8, 2009

Summary

Genomics is revolutionizing veterinary oncology by providing new insights into comparative cancer research. This technology enhances the evaluation and treatment of cancer in companion animals, aligning with the "one medicine" approach.

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Area of Science:

Veterinary Medicine
Genomics
Comparative Oncology

Background:

Advances in human genomics have spurred progress in veterinary species.
Comparative genomics offers insights into shared disease pathways between humans and animals.
The
one medicine
concept highlights the interdependence of human and veterinary research.

Purpose of the Study:

To review advancements in genomics relevant to veterinary oncology.
To explore the impact of genomics on understanding and treating animal cancers.
To discuss the role of companion animals as models in comparative oncology.

Main Methods:

Review of current genomics technologies and their applications.
Analysis of shared pathogenetic bases in human and animal diseases.
Examination of data derived from genomics in veterinary oncology.

Main Results:

Genomics is significantly advancing veterinary oncology.
Comparative genomics provides a framework for understanding complex diseases.
Genomic data is transforming patient evaluation and treatment strategies.

Conclusions:

Genomics is essential for the future of veterinary oncology.
The integration of genomics will lead to improved outcomes for companion animal cancer patients.
The
one medicine
approach is crucial for advancing both human and veterinary cancer research.