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Dimethyl trisulfide as a characteristic odor associated with fungating cancer wounds

Mika Shirasu1, Shunji Nagai, Ryuichi Hayashi

  • 1Department of Integrated Biosciences, The University of Tokyo, Chiba 277-8562, Japan.

Bioscience, Biotechnology, and Biochemistry
|September 8, 2009
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Sulfides are the sulfur analog of ethers, just as thiols are the sulfur analog of alcohol. Like ethers, sulfides also consist of two hydrocarbon groups bonded to the central sulfur atom. Depending upon the type of groups present, sulfides can be symmetrical or asymmetrical. Symmetrical sulfides can be prepared via an SN2 reaction between 2 equivalents of an alkyl halide and one equivalent of sodium sulfide.