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Updated: Jun 20, 2026

Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis
Published on: July 18, 2017
[Emphysematous pyelonephritis. Case report]
Tristán Dellavedova1, María Laura Racca, Rolando Ponzano
1FUCDIM (Fundación Urológica Córdoba para la Docencia e Investigación Médica), Cordoba, Argentina. trisdellavedova@hotmail.com
Objective:
To describe an unusual case of emphysematous pyelonephritis, a disease with high morbidity and mortality.
Methods:
We present the case of a 62-year old diabetic female with history of kidney stones, who consulted for fever, left lower-back pain and impairment of the general condition. Abdominopelvic computed tomography revealed a perinephric collection of air reaching the abdominal wall.
Results:
After initial medical management with antibiotics and general supportive measures, we performed an open incision and drainage. A week later, signs of sepsis reappeared and the left kidney was excised. The patient died two weeks later of septic shock.
Conclusions:
This disease must be suspected in diabetic females with renal lithiasis and pyelonephritis not responding to treatment, and impaired general condition. Early diagnosis (computed tomography is the gold-standard) and supportive measures are essential for initial management. Surgery can be open (drainage, initial or deferred nephrectomy), percutaneous (nephrostomy) or endoscopic (double-J stent). Conservative management is a choice in bilateral or mild cases. Mortality rate is high and worsens with delayed therapy.
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