Related Experiment Video
Updated: Jun 20, 2026
08:03
Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
Craniofacial features in Goldenhar syndrome
C Vinay1, R Sudhakara Reddy, K S Uloopi
1Department of Pedodontics and Preventive Dentistry, Vishnu Dental College and Hospital, Bhimavaram - 534202, Andhra Pradesh, India. vinaychandrappa@yahoo.co.in
Journal of the Indian Society of Pedodontics and Preventive Dentistry
|September 9, 2009
Summary
Goldenhar syndrome, a rare oculo-auriculo-vertebral condition, presents with craniofacial and vertebral anomalies. This case report details a 12-year-old male patient diagnosed with this sporadic disorder.
Area of Science:
- Medical Genetics
- Developmental Biology
- Pediatric Medicine
Background:
- Goldenhar syndrome, also known as oculo-auriculo-vertebral spectrum, is a rare congenital disorder.
- It is characterized by a spectrum of anomalies affecting the craniofacial region and vertebrae.
- The exact etiology remains largely unknown, and it typically occurs sporadically.
Observation:
- This report focuses on a 12-year-old male patient.
- The patient presented with typical craniofacial malformations associated with Goldenhar syndrome.
- Specific anomalies included mandibular hypoplasia, malar bone hypoplasia, and microtia.
Findings:
- The diagnosis of Goldenhar syndrome was confirmed in the pediatric patient.
- The case highlights the characteristic features of this rare disease entity.
- Vertebral anomalies, a key diagnostic criterion, were also noted.
Implications:
- This case contributes to the understanding of Goldenhar syndrome presentation in pediatric populations.
- Further research into the etiology of oculo-auriculo-vertebral spectrum is warranted.
- Accurate diagnosis and management of craniofacial and vertebral anomalies are crucial for affected individuals.
Related Concept Videos
01:27Cranial Bones: Lateral View
The lateral view of the cranium is dominated by temporal, sphenoid, and ethmoid bones.
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
01:24Prosopagnosia
Prosopagnosia, also known as face blindness, is the inability to recognize faces. In severe cases, individuals with prosopagnosia may not recognize close family members, including parents and spouses, by their faces. For instance, someone with prosopagnosia might walk past their child in a crowd, only realizing their mistake upon noticing their child's distinctive backpack or favorite jacket. Prosopagnosia specifically impairs facial recognition, while the recognition of other objects or...
01:14Cranial Bones: Superior and Posterior View
The superior view of the cranium shows the frontal and paired parietal bones.
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
01:08Overview of the Skull
The cranium (skull) is the skeletal structure of the head that supports the face and protects the brain. It is subdivided into the facial bones and the brain case, or cranial vault. The facial bones underlie the facial structures, form the nasal cavity, enclose the eyeballs, and support the teeth of the upper and lower jaws.
The cranial vault surrounds and protects the brain and houses the middle and inner ear structures. This cavity is bounded superiorly by the rounded top of the skull, which...
The cranial vault surrounds and protects the brain and houses the middle and inner ear structures. This cavity is bounded superiorly by the rounded top of the skull, which...
01:14Muscles for Facial Expressions
The craniofacial muscles are a collection of approximately 20 thin skeletal muscles situated beneath the skin of the face and scalp. These muscles, primarily responsible for the vast array of human facial expressions, originate from the bones or fibrous structures of the skull and extend outwards to connect with the skin. While most skeletal muscles in the body are enveloped in thick fascia, facial muscles generally have a more delicate fascial covering, with the buccinator muscle being a...
01:22Sutures of the Skull
The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...