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A novel HLA-Cw*04 allele, Cw*04010103, identified by genomic full length cloning and sequencing

Y Xu1, Z Deng, J Zeng

  • 1Key Laboratory of Shenzhen for Histocompatibility and Immunogenetics, Shenzhen Blood Center, Shenzhen, PR China. yunpingxu1982@yahoo.com.cn

Tissue Antigens
|September 10, 2009
PubMed

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Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...