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Identification of HLA-B*9521 in Taiwan

C-C Chu1, Y-F Chen, H-L Lee

  • 1Transfusion Medicine Laboratory, Department of Medical Research, Mackay Memorial Hospital, Taiwan.

Tissue Antigens
|September 10, 2009
PubMed

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Single Nucleotide Polymorphisms-SNPs01:05

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A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...