Short- and long-term outcomes of percutaneous coronary interventions in patients with severe left ventricular

Imad Sheiban1, Claudio Moretti, Giuseppe Biondi Zoccai

  • 1Interventional Cardiology, Division of Cardiology, University of Torino, San Giovanni Battista Hospital, Torino, Italy.

Insights

Percutaneous coronary intervention (PCI) offers excellent procedural success for patients with coronary artery disease and severe left ventricular dysfunction. Long-term outcomes show acceptable morbidity and mortality, making PCI a viable option.

Area of Science:

  • Cardiology
  • Interventional Cardiology

Background:

  • Severe left ventricular dysfunction (EF < 30%) poses high risk for revascularization procedures.
  • Coronary artery disease (CAD) with impaired left ventricular function requires careful treatment strategies.

Purpose of the Study:

  • To assess the immediate and long-term results of percutaneous coronary intervention (PCI) in patients with CAD and severe left ventricular dysfunction.
  • To evaluate the safety and efficacy of PCI in a high-risk patient cohort.

Main Methods:

  • Seventy-eight patients with CAD and EF < 30% underwent PCI.
  • Analysis of procedural success, adverse events, and long-term follow-up outcomes.
  • Identification of independent predictors for mortality and major adverse cardiac events (MACE).

Main Results:

  • High procedural success rate (97.8%) with low in-hospital adverse events (7.8%).
  • At a mean follow-up of 25 months, event-free survival was 55%, with 27.6% requiring repeat revascularization.
  • Female gender, diabetes, myocardial infarction, and treated vessel count predicted adverse outcomes.

Conclusions:

  • PCI is a safe and effective option for symptomatic patients with CAD and severe left ventricular dysfunction.
  • The procedure demonstrates excellent procedural success and acceptable long-term morbidity and mortality.
Abstract

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