Related Experiment Video

Updated: Jun 20, 2026

Analysis of Zebrafish Larvae Skeletal Muscle Integrity with Evans Blue Dye
07:34

Analysis of Zebrafish Larvae Skeletal Muscle Integrity with Evans Blue Dye

Published on: November 30, 2015

A blue baby grows up

Jamil A Aboulhosn1, John S Child

  • 1Ahmanson/UCLA Adult Congenital Heart Disease Center, Los Angeles, Calif 90095-1679, USA. jaboulhosn@mednet.ucla.edu

Congenital Heart Disease
|September 11, 2009
PubMed

Insights

This case report details a 41-year-old adult with complex congenital heart disease, focusing on pulmonary arterial hypertension management. It highlights clinical challenges in caring for adults with palliated cyanotic heart conditions.

Area of Science:

  • Cardiology
  • Pediatric Cardiology
  • Adult Congenital Heart Disease

Background:

  • Complex congenital heart disease (CCHD) requires lifelong management.
  • Palliative surgical interventions in infancy can lead to long-term complications.
  • Pulmonary arterial hypertension (PAH) is a significant concern in adults with CCHD.

Observation:

  • A 41-year-old female with multiple congenital heart defects, including atresia of the right atrioventricular valve and malposed great arteries, presented with PAH.
  • The patient had undergone pulmonary artery banding in infancy but did not receive corrective surgery due to PAH development.

Findings:

  • Pulmonary arterial hypertension (PAH) can develop or progress in adults with complex, palliated congenital heart disease.
  • Management of PAH in this population presents unique clinical challenges.
  • This case underscores the importance of monitoring and managing PAH in adults with CCHD.

Implications:

  • Adult congenital heart disease (ACHD) programs must address the complexities of PAH.
  • Early recognition and tailored treatment strategies are crucial for improving outcomes in adults with CCHD and PAH.
  • Further research is needed to optimize PAH management in the ACHD population.

More Related Videos

Hand-Rearing Method for Infant Marmosets04:52

Hand-Rearing Method for Infant Marmosets

Published on: June 9, 2023

A Protocol for Laboratory Housing of Turquoise Killifish (Nothobranchius furzeri)07:58

A Protocol for Laboratory Housing of Turquoise Killifish (Nothobranchius furzeri)

Published on: April 11, 2018

Related Concept Videos

Oxygen Requirements and Growth Patterns01:29

Oxygen Requirements and Growth Patterns

Microorganisms exhibit diverse oxygen requirements and growth patterns driven by their metabolic strategies and environmental adaptations. Oxygen, while essential for many organisms, can also be toxic under certain conditions, shaping how microorganisms grow and survive.Oxygen Requirements of MicroorganismsMicroorganisms are classified based on their ability to use or tolerate oxygen:● Obligate aerobes like Mycobacterium tuberculosis need oxygen for energy production, as it serves as the...
Conservation of Declining Populations02:07

Conservation of Declining Populations

Conservation of declining population focuses on ways of detecting, diagnosing, and halting a population decline. The approach uses methods to prevent populations from going extinct.
Parental Care00:55

Parental Care

Many animals exhibit parental care behavior, including feeding, grooming, and protecting young offspring. Parental care is universal in mammals and birds, which often have young that are born relatively helpless. Several species of insects and fish, as well as some amphibians, also care for their young.
Fetal Circulation01:14

Fetal Circulation

Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Cloning of Dolly the Sheep01:08

Cloning of Dolly the Sheep

The first successfully cloned mammal was Dolly, a sheep, born on 5th July 1996 at Roslin Institute, Scotland. The cloned sheep was named after the American singer Dolly Parton. Dolly lived for seven years and died of respiratory complications, which is speculated to be due to the actual age of her DNA. Because the DNA in cloned cells belongs to an older individual,  the cloned individual’s life expectancy may be affected. Indeed, analysis of Dolly’s DNA revealed shorter telomeres than other...
Gastrulation01:56

Gastrulation

Gastrulation establishes the three primary tissues of an embryo: the ectoderm, mesoderm, and endoderm. This developmental process relies on a series of intricate cellular movements, which in humans transforms a flat, “bilaminar disc” composed of two cell sheets into a three-tiered structure. In the resulting embryo, the endoderm serves as the bottom layer, and stacked directly above it is the intermediate mesoderm, and then the uppermost ectoderm. Respectively, these tissue strata will form...