Transcatheter interventions in adult patients with transposition of the great arteries

Transposition of the great arteries (TGA) is a complex congenital heart defect with two primary anatomical subtypes: dextro-TGA and levo-TGA. Advances in neonatal surgical techniques, particularly the arterial switch operation, have significantly improved survival rates. However, as this population ages, late complications such as heart failure and valve dysfunction present new clinical challenges. Transcatheter interventions have emerged as valid alternatives to surgical reintervention for these patients, providing effective symptom relief and improved quality of life, reducing the need for repeated sternotomies. As more adults with repaired TGA reach advanced ages, long-term studies are needed to assess the durability and safety of transcatheter therapies. Expanding the indications, refining procedural techniques, and developing specialized devices will be essential in optimizing outcomes for this growing patient population.