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[Risk factors associated with upper gastrointestinal bleeding and with mortality]
Heriberto Rodríguez-Hernández1, Martha Rodríguez-Morán, José Luis González
1Unidad de Investigación Médica, Instituto Mexicano del Seguro Social, Durango, Durango, Mexico.
Revista Medica Del Instituto Mexicano Del Seguro Social
|September 12, 2009
Summary
Smoking, alcohol use, and a history of upper gastrointestinal bleeding (UGIB) significantly increase risks in peptic ulcer patients. Chronic obstructive pulmonary disease and high blood pressure are linked to mortality in UGIB cases.
Area of Science:
- Gastroenterology
- Internal Medicine
- Epidemiology
Background:
- Peptic ulcer disease is a common condition with potential complications like upper gastrointestinal bleeding (UGIB).
- Identifying risk factors for UGIB and associated mortality is crucial for patient management and preventive strategies.
Purpose of the Study:
- To determine the risk factors associated with upper gastrointestinal bleeding (UGIB) in patients with peptic ulcers.
- To identify factors linked to mortality in peptic ulcer patients experiencing UGIB.
Main Methods:
- A cross-sectional study involving 345 peptic ulcer patients under 60 years old.
- Logistic regression analysis, adjusted for age and sex, was employed to assess risk factors for UGIB and mortality.
Main Results:
- Smoking (OR=2.6), alcohol consumption (OR=4.8), and a prior history of UGIB (OR=1.8) were independently associated with UGIB.
- Chronic obstructive pulmonary disease (OR=1.9) and hypertension (OR=1.4) were associated with mortality in patients with UGIB.
Conclusions:
- Key risk factors for UGIB in peptic ulcer patients include being under 60, smoking, previous UGIB, and alcohol consumption.
- Chronic obstructive pulmonary disease and hypertension are identified as factors associated with mortality in the context of UGIB.
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