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Updated: Jun 20, 2026

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
Published on: September 20, 2024
Thyroid surgery in octogenarians is associated with higher complication rates.
Michal Mekel1, Antonia E Stephen, Randall D Gaz
1Department of Surgery and Endocrine Surgery Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
Thyroid surgery in patients aged 80 and older has a higher complication rate than in younger patients. However, age alone is not an independent risk factor for complications after thyroid surgery.
Area of Science:
- Endocrinology
- Surgical Oncology
- Geriatric Medicine
Background:
- Thyroid nodules are increasingly common with age.
- Limited data exists on the risks of thyroid surgery in elderly individuals.
- This study investigates complication rates in octogenarian thyroid surgery patients.
Purpose of the Study:
- To determine if thyroid surgery in patients aged 80 years or older is linked to increased complication rates.
- To identify risk factors associated with thyroid surgery complications in the elderly.
Main Methods:
- Retrospective review of 90 patients aged 80+ undergoing thyroid surgery.
- Comparison with 242 younger patients (18-79) undergoing thyroid surgery.
- Analysis of clinical variables including comorbidities, ASA score, and postoperative outcomes.
Main Results:
- Octogenarians had a 24% overall complication rate versus 9% in younger patients (P < .001).
- Malignancy was found in 20% of octogenarians versus 27% of younger patients (P = NS).
- Male gender and ASA score of 3 or higher were independent risk factors for complications.
Conclusions:
- While age 80+ is associated with higher morbidity, it is not an independent risk factor.
- Consider earlier surgery for high-risk patients and non-operative management for others.
- Risk stratification is crucial for optimizing thyroid surgery outcomes in the elderly.
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