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Updated: Jun 20, 2026

Mouse Model of Acute to Chronic Kidney Disease Transition Induced by Renal Ischemia/Reperfusion Injury
Published on: February 10, 2026
Contrast-induced acute kidney injury (CIAKI)
1Department of Medicine, University of Vermont School of Medicine, 1 South Prospect Street, Burlington, VT 05401, USA. richard.solomon@vtmednet.org
Abstract:
Injury to the kidney continues to occur following the administration of intravascular iodinated contrast media. In this article, the author reviews the pathophysiology of contrast-induced acute kidney injury (CIAKI), the relationship of CIAKI to long-term adverse outcomes, what type of patients are at risk of CIAKI, and how the diagnosis is made. After discussion of the reported incidence of CIAKI, an approach to prevention is briefly reviewed.
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