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A case of organizing pneumonia associated with rituximab
Chi Hoon Maeng1, Sang Ouk Chin, Byung Hyuk Yang
1Department of Internal Medicine, Kyung Hee University College of Medicine, Seoul, Korea.
Abstract:
Rituximab is a human/murine chimeric anti-CD20 monoclonal antibody used to treat CD20-positive B-cell non-Hodgkin's lymphoma (NHL). Although most of the adverse effects associated with rituximab are usually reversible and temporary infusion-related reactions, including fever, chills, flushing and skin reactions, there are several reports of pulmonary events after long-term administration of rituximab. We present a case of asymptomatic nodular organizing pneumonia occurring during rituximab-based chemotherapy in a patient with non-Hodgkin's lymphoma.
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