A scheme for multisource interior tomography
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Updated: Jun 20, 2026

Rapid Setup of Tissue Microarray and Tiled Area Imaging on the Multiplexed Ion Beam Imaging Microscope Using the Tile/SED/Array Interface
Published on: September 15, 2023
Ge Wang1, Hengyong Yu, Yangbo Ye
1Biomedical Imaging Division, VT-WFU School of Biomedical Engineering and Sciences, Virginia Tech., Blacksburg, Virginia 24061, USA. wangg@vt.edu
Abstract:
Currently, x-ray computed tomography (CT) requires source scanning so that projections can be collected from various orientations for image reconstruction. Limited by the scanning time, the temporal resolution of CT is often inadequate when rapid dynamics is involved in an object to be reconstructed. To meet this challenge, here the authors propose a scheme of multisource interior tomography for ultrafast imaging that reconstructs a relatively small region of interest (ROI). Specifically, such a ROI is irradiated in parallel with narrow x-ray beams defined by many source-detector pairs for data acquisition. This ROI can be then reconstructed using the interior tomography approach. To demonstrate the merits of this approach, the authors report interior reconstruction from in vivo lung CT data at a much reduced radiation dose, which is roughly proportional to the ROI size. The results suggest a scheme for ultrafast tomography (such as with a limited number of sources and in a scanning mode) to shorten data acquisition time and to suppress motion blurring.
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