Related Experiment Video
Updated: Jun 20, 2026

Natural Product Discovery with LC-MS/MS Diagnostic Fragmentation Filtering: Application for Microcystin Analysis
Published on: May 31, 2019
Isolation of a Methylobacillus sp. that degrades microcystin toxins associated with cyanobacteria
Liang Bin Hu1, Jing Dong Yang, Wei Zhou
1School of Food, Henan Institute of Science and Technology, Xinxiang 453003, China.
Abstract:
Sludge from cyanobacteria-salvaged yard in Meiliang Bay, Lake Taihu in Wuxi, China was cultured and acclimated by inoculating microcystins (MCs) extract. Strain J10 was isolated by degrading the MC-RR and MC-LR and was identified as Methylobacillus sp. Further research showed that both MC-LR and MC-RR could be completely degraded at 17h after inoculation of J10, and the degradation probably was mediated by oxygen. Different enzymes, oxygen-dependent as well as oxygen-independent, with MC-degrading activity were found in the different fractions of J10 culture. However, the enzymes mainly responsible for MC degradation by J10 were oxygen-dependent and were probably bound to cell wall or outside the cytoplasmic membrane.
More Related Videos
Related Concept Videos
Microbial Mats
Bioremediation
Bacterial Phylum Cyanobacteria
Techniques for Isolation of Pure Cultures
Microbial Bioremediation of Hydrocarbons

