Related Experiment Video
Updated: Jun 20, 2026

05:46
Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
Published on: December 2, 2022
[Orbital metastasis from cutaneous melanoma]
F Ben Hadj Hamida1, M Fezani, H Ben Amor
1Service d'ophtalmologie, Centre hospitalo universitaire Farhat Hached, Sousse, Tunisie. fafani.benhamida@rns.tn
Journal Francais D'Ophtalmologie
|September 15, 2009
Summary
Orbital metastasis from cutaneous melanoma is rare, often a late-stage diagnosis with a poor prognosis. This case highlights diagnostic challenges and the aggressive nature of melanoma spread.
Area of Science:
- Ophthalmology
- Oncology
- Medical Imaging
Background:
- Cutaneous melanoma can rarely metastasize to the orbit.
- Orbital metastases often indicate advanced disease.
Observation:
- A 70-year-old woman presented with unilateral proptosis and decreased vision.
- Imaging revealed an intraorbital mass consistent with metastasis.
- The patient had a history of melanoma and diffuse metastases.
Findings:
- Computed tomography (CT) and magnetic resonance imaging (MRI) characterized the orbital mass.
- Diagnosis was complicated by the patient's late presentation and widespread disease.
Implications:
- Cutaneous melanoma is an uncommon cause of orbital metastasis.
- Early detection and treatment are crucial for improving prognosis in melanoma patients.
- Orbital metastasis from melanoma carries a poor life expectancy, typically less than one year.
Related Concept Videos
Skin Cancer
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Metastasis
Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Metastasis
Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
