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DNA Packaging

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Eukaryotic Compartmentalization

Eukaryotic Compartmentalization

One of the distinguishing features of eukaryotic cells is that they contain membrane-bound organelles, such as the nucleus and mitochondria, that carry out specialized functions. Since biological membranes are only selectively permeable to solutes, they help create a compartment with controlled conditions inside an organelle. These microenvironments are tailored to the organelle's specific functions and help isolate them from the surrounding cytosol.
For example, lysosomes in the animal cells...

Eukaryotic Compartmentalizations

Eukaryotic Compartmentalizations

One of the distinguishing features of eukaryotic cells is that they contain membrane-bound organelles, such as the nucleus and mitochondria, that carry out specialized functions. Since biological membranes are only selectively permeable to solutes, they help create a compartment with controlled conditions inside an organelle. These microenvironments are tailored to the organelle's specific functions and help isolate them from the surrounding cytosol.
For example, lysosomes in the animal cells...

Genomic DNA in Eukaryotes

Genomic DNA in Eukaryotes

Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.

Molecular Shapes

Molecular Shapes

Molecules have characteristic shapes that are crucial for their function. The arrangement of various electron groups around the central atom dictates their molecular geometry. Electron pairs in the valence shell of a central atom will adopt an arrangement that minimizes repulsions between the electron pairs by maximizing the distance between them. The valence electrons form either bonding pairs, located primarily between bonded atoms, or lone pairs.Two regions of electron density in a diatomic...

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Updated: Jun 20, 2026

Preparation of Multifunctional Silk-Based Microcapsules Loaded with DNA Plasmids Encoding RNA Aptamers and Riboswitches

Preparation of Multifunctional Silk-Based Microcapsules Loaded with DNA Plasmids Encoding RNA Aptamers and Riboswitches

Published on: October 8, 2021

Molecular encapsulation.

Fraser Hof¹, Stephen L Craig, Colin Nuckolls

¹The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

Angewandte Chemie (International Ed. in English)

|September 16, 2009

Summary

This summary is machine-generated.

Molecules can self-assemble into complex structures, forming aggregates that surround other molecules. These molecular aggregates exhibit emergent properties and functions not present in individual components.

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Last Updated: Jun 20, 2026

Preparation of Multifunctional Silk-Based Microcapsules Loaded with DNA Plasmids Encoding RNA Aptamers and Riboswitches

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Published on: October 8, 2021

Assembly and Characterization of Polyelectrolyte Complex Micelles

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Directed Assembly of Elastin-like Proteins into defined Supramolecular Structures and Cargo Encapsulation In Vitro

Directed Assembly of Elastin-like Proteins into defined Supramolecular Structures and Cargo Encapsulation In Vitro

Published on: April 8, 2020

Area of Science:

Supramolecular Chemistry
Materials Science

Background:

Molecules naturally aggregate to form complex structures.
These aggregates exhibit emergent properties and functions.
Self-assembly is a key principle in molecular organization.

Purpose of the Study:

To review molecular aggregates that surround other molecules.
To explore the unique properties and functions of these aggregates.
To emphasize self-complementary structures in molecular assembly.

Main Methods:

Review of literature on molecular aggregation.
Focus on self-complementary structures.
Analysis of engineered molecular instructions for assembly.

Main Results:

Molecular aggregation leads to new properties and functions.
Self-complementary structures play a crucial role in assembly.
Engineered molecular designs dictate self-assembly behavior.

Conclusions:

Molecular aggregates exhibit unique properties beyond individual components.
Self-assembly is driven by inherent molecular design.
Understanding molecular aggregation is key to designing novel materials.