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Urethral instability: current pathophysiological concept.
P M Groenendijk1, J P F A Heesakkers, T J Ouwerkerk
1Department of Urology, Leiden University Medical Center, Leiden, The Netherlands. groenenp@rdgg.nl
Urologia Internationalis
|September 16, 2009
Summary
Urethral pressure variations during cystometry are often overlooked but may explain voiding and storage dysfunctions. Recognizing urethral instability aids in diagnosing and treating lower urinary tract disorders.
Area of Science:
- Urology
- Urodynamics
- Functional Lower Urinary Tract Disorders
Background:
- Urethral pressure variations during filling cystometry are rarely assessed.
- These variations may contribute to voiding dysfunction and storage disorders.
Purpose of the Study:
- To review current research on urethral pressure variations.
- To discuss methods for determining these variations and their clinical value.
- To hypothesize the origins of urethral pressure variations.
Main Methods:
- Literature review of current research on urethral pressure variations.
- Discussion of diagnostic methods and clinical applications.
- Hypothetical analysis of the origins of urethral pressure variations.
Main Results:
- Urethral pressure variations are an under-recognized factor in lower urinary tract symptoms.
- Methods for assessing urethral pressure variations exist and have clinical relevance.
- Potential origins of urethral pressure variations are explored.
Conclusions:
- Recognizing urethral pressure variations (urethral instability) is important.
- This recognition can aid in diagnosing and evaluating treatment for functional lower urinary tract disorders.
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