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Updated: Jun 20, 2026

An Ex Vivo Model of Ovarian Cancer Peritoneal Metastasis Using Human Omentum
Published on: January 26, 2024
Umbilical metastasis of serous component as a first sign of mixed type epithelial ovarian cancer
S Kurt1, H Camuzcuoglu, A Camuzcuoglu
1Division of Gynecologic Oncology, Department of Obstetrics & Gynecology, Aegean Maternity and Women's Health Hospital, Izmir, Turkey.
Abstract:
Umbilical metastasis (Sister Mary Joseph's nodule) of malignant neoplasms is a rare condition. These nodules usually arise from the gastrointestinal or genitourinary tract and may present the first sign of a previously unknown primary tumor. We describe a 49-year-old woman presenting with Sister Mary Joseph's nodule as the first sign of an extremely aggressive Stage IV mixed type epithelial ovarian carcinoma, who died 15 months after the initial diagnosis. This is the first case of a Sister Mary Joseph's nodule from a serous component of a Stage IV mixed type epithelial ovarian cancer.
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