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Generic binding sites, generic DNA-binding domains: where does specific promoter recognition come from?

Adrien B Georges1, Bérénice A Benayoun, Sandrine Caburet

  • 1Unité Mixte de Recherche 7592-Centre National de la Recherche Scientifique, Institut Jacques Monod, Paris, France.

FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology
|September 19, 2009
PubMed
Summary

Transcription factors (TFs) achieve specific gene regulation through cooperative binding to DNA. Complex protein structures, like enhanceosomes, integrate information for precise control of gene expression.

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