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An Efficient Sieving Method to Isolate Intact Glomeruli from Adult Rat Kidney
Published on: November 1, 2018
Glomerular disease in the elderly
1The David Geffen School of Medicine at UCLA, 8 Bethany, Laguna Niguel, Los Angeles, CA 92677, USA. glassock@cox.net
Insights
Chronic glomerular disease significantly impacts elderly health, causing disability and death. This review covers primary and secondary kidney diseases in older adults, detailing their presentation, prognosis, and management.
Area of Science:
- Nephrology
- Geriatric Medicine
- Internal Medicine
Background:
- Chronic glomerular disease is a leading cause of morbidity and mortality in the elderly population.
- Causes are diverse, categorized into primary glomerular diseases and secondary glomerular diseases (systemic processes).
Purpose of the Study:
- To outline common presentations of glomerular disease in the elderly.
- To discuss clinical features, prognosis, and management strategies for primary and secondary glomerular diseases in this demographic.
Main Methods:
- Review of existing literature on chronic glomerular disease in the elderly.
- Synthesis of information regarding clinical presentations, diagnostic features, and therapeutic approaches.
Main Results:
- Glomerular diseases in the elderly present with varied clinical manifestations.
- Distinguishing between primary and secondary causes is crucial for appropriate management and prognosis.
Conclusions:
- Effective management of chronic glomerular disease in the elderly requires understanding its diverse etiologies and tailored treatment strategies.
- Early recognition and intervention can improve outcomes and reduce mortality associated with these kidney conditions.
Abstract:
Chronic glomerular disease is a common cause of disability and mortality in the elderly. The underlying cause of the glomerular disease in this population is diverse but can generally be divided into those that affect the kidneys primarily (primary glomerular disease) and those in which the kidney damage is a part of a systemwide process (secondary glomerular disease). This article briefly outlines the common presentations of glomerular disease in the elderly and discusses the clinical features, prognosis, and management of the primary and secondary glomerular diseases in this population of patients.
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