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A prospective study in children: Pre- and post-surgery use of vitamin E in surgical incisions

Nicola Zampieri1, Veronica Zuin, Roberto Burro

  • 1Department of Surgical Sciences, Pediatric Surgical Unit, University of Verona, Policlinico G.B.Rossi, Piazzale L.A. Scuro n. 1, Verona, Italy. dr.zampieri@libero.it

Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS
|September 22, 2009
PubMed

Insights

Topical vitamin E significantly improved cosmetic surgical outcomes in children. This treatment reduced keloid formation and enhanced overall patient satisfaction with surgical wound healing.

Area of Science:

  • Dermatology
  • Pediatric Surgery
  • Wound Healing Research

Background:

  • Poor cosmetic results are a significant concern in elective pediatric surgery.
  • Optimizing surgical outcomes, particularly aesthetic results, remains a key challenge.

Purpose of the Study:

  • To investigate the efficacy of topical vitamin E in improving cosmetic results of surgical incisions in children.
  • To compare the effects of topical vitamin E versus a petrolatum-based ointment on surgical wound healing and appearance.

Main Methods:

  • A prospective, single-blind, controlled study was conducted.
  • Group A received topical vitamin E pre- and post-surgery (15 days before, 30 days after).
  • Group B (control) received a petrolatum-based ointment.

Main Results:

  • No keloid formation was observed in the vitamin E group (Group A).
  • 96% of patients/parents reported very good cosmetic results in Group A.
  • The control group (Group B) had a 6.5% keloid rate and 78% very good cosmetic results.

Conclusions:

  • Pre- and post-operative topical vitamin E application enhances surgical wound healing.
  • Topical vitamin E significantly improves the cosmetic outcomes of surgical incisions in pediatric patients.
Abstract

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