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Updated: Jun 20, 2026

An Ex Vivo Porcine Model for Hydrodynamic Testing of Experimental Aortic Valve Procedures and Novel Medical Devices
Published on: August 25, 2023
Failure of percutaneous closure of prosthetic, aortic paravalvular leak
Evaristo Castedo1, Santiago Serrano-Fiz, Juan F Oteo
1Department of Cardiothoracic Surgery, Hospital Universitario Puerta de Hierro Majadahonda, Universidad Autonoma de Madrid, Madrid, Spain. evaristocm@terra.es
Abstract:
We report the progression of aortic insufficiency after percutaneous closure of an aortic prosthesis paravalvular leak with the Amplatzer vascular plug (AGA Inc, Golden Valley, MN). Removal of the device and replacement of the aortic prosthesis was successfully performed. Based on operative findings, we hypothesize that shape mismatch between the occluder system and the leak might promote tearing at the end of slanted defects further enhancing the regurgitant area.
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