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Updated: Jun 20, 2026

A Time-Efficient Fluorescence Spectroscopy-Based Assay for Evaluating Actin Polymerization Status in Rodent and Human Brain Tissues
06:54

A Time-Efficient Fluorescence Spectroscopy-Based Assay for Evaluating Actin Polymerization Status in Rodent and Human Brain Tissues

Published on: June 3, 2021

Functional analysis of actin-binding proteins in the central nervous system of Drosophila

Qi He1

  • 1Department of Biology, Brooklyn College-CUNY, Brooklyn, NY, USA.

Methods in Molecular Biology (Clifton, N.J.)
|September 22, 2009
PubMed

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Actin Polymerization and Cell Motility

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Formation of Higher-order Actin Filaments

The polymerization of G-actin monomers into filamentous F-actin is a multi-step process. Once the F-actins are formed, they can bundle together in different arrangements to form higher-order networks and regulate cellular functions. Common examples include the formation of lamellipodia and filopodia at the cell's leading edge by actin reorganization in a migrating cell. The microvilli on the brush border epithelial cells are also formed through the F-actin network.
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Cytoskeletal Accessory Proteins

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Actin Filament Depolymerization

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