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Updated: Jun 20, 2026

Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia
Published on: February 17, 2023
[Primary insomnia]
Yuhei Kayukawa1, Tsuyoshi Kitajima, Satoe Tomita
1Nagoya Institute of Technology, Health Support Center.
Primary insomnia, a common sleep disorder, involves persistent issues with sleep initiation, maintenance, or quality, impacting daily life. Current research suggests a hyperarousal hypothesis may explain this condition.
Area of Science:
- Sleep Medicine
- Neurology
- Psychiatry
Context:
- Primary insomnia is a prevalent sleep disorder affecting sleep initiation, maintenance, or quality.
- It is diagnosed when sleep disturbances persist over three weeks and impair daytime functioning.
- This condition is distinct from insomnia caused by other medical or psychiatric disorders.
Purpose:
- To define primary insomnia based on The International Classification of Sleep Disorders.
- To explore the characteristics and potential causes of primary insomnia.
- To discuss the evolving understanding of primary insomnia, including the hyperarousal hypothesis.
Summary:
- Primary insomnia encompasses psychophysiological, paradoxical, and idiopathic insomnia.
- Key symptoms include difficulty falling asleep, staying asleep, or experiencing non-restorative sleep.
- It predominantly affects middle-aged females and is not attributed to other known conditions.
Impact:
- Highlights the hyperarousal hypothesis as a leading explanation for primary insomnia.
- Suggests potential future revisions to the definition of primary insomnia, possibly excluding non-restorative sleep.
- Emphasizes the need for further research into the etiology and treatment of this common sleep disorder.
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