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Related Concept Videos

Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
The Skin Microbiota01:27

The Skin Microbiota

The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...
Healing II: Complications01:24

Healing II: Complications

Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...

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Related Experiment Video

Updated: Jun 20, 2026

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses
10:45

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses

Published on: June 13, 2018

Skin and soft tissue abscess: 1 year's experience.

Sandhya Nalmas, Eliahu Bishburg, Monica Shah

    Journal of Cutaneous Medicine and Surgery
    |September 23, 2009
    PubMed
    Summary

    Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is a growing cause of skin and soft tissue abscesses (SSTAs). Multiple abscesses and their location significantly influence inpatient treatment decisions, unlike fever alone.

    Related Experiment Videos

    Last Updated: Jun 20, 2026

    Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses
    10:45

    Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses

    Published on: June 13, 2018

    Area of Science:

    • Infectious Diseases
    • Dermatology
    • Public Health

    Background:

    • Rising incidence of skin and soft tissue abscesses (SSTAs) linked to community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA).
    • Patients with SSTAs are managed as either outpatients (OPs) or inpatients (IPs).

    Purpose of the Study:

    • To investigate the microbiology and clinical characteristics of SSTAs.
    • To identify clinical parameters influencing the decision to admit SSTA patients as IPs.

    Main Methods:

    • Retrospective chart review of 138 SSTA patients from January to December 2005.
    • Data collected included demographics, comorbidities, SSTA details, and clinical presentation.
    • Analysis focused on factors differentiating inpatient and outpatient treatment groups.

    Main Results:

    • CA-MRSA was the predominant organism, particularly in outpatients.
    • Common SSTA sites included the perineal area, extremities, and head/neck.
    • Factors statistically associated with inpatient admission were SSTA number and site.

    Conclusions:

    • SSTA number and anatomical site are key determinants for inpatient admission.
    • While fever was noted, its statistical significance in admission decisions was not confirmed.
    • Understanding these factors can optimize patient management strategies for SSTAs.