Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Pharyngitis01:23

Chronic Pharyngitis

Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Nose and Nasal Cavity01:24

Nose and Nasal Cavity

The nose is composed of an observable exterior segment (external nose) and an internal segment within the skull known as the nasal cavity (internal nose). The external nose, visible on the face, consists of a framework of bone and hyaline cartilage enveloped in skin and muscle and lined with a mucous membrane. This structure is supported by the frontal bone, nasal bones, and maxillary bone and is supplemented by a cartilaginous framework comprising the septal nasal cartilage, lateral nasal...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Pharynx01:20

Pharynx

The pharynx, a tubular structure framed by skeletal muscle and lined with mucous membrane, extends continuously from the nasal cavities. It is segmented into three major areas: the nasopharynx, oropharynx, and laryngopharynx.
Nasopharynx
The nasopharynx, bordered by the conchae of the nasal cavity, serves exclusively as an air conduit. In its superior region, the pharyngeal tonsils or adenoids are located. These tonsils are clusters of lymphoid reticular tissue akin to a lymph node. The precise...
Olfactory Receptors: Location and Structure01:03

Olfactory Receptors: Location and Structure

The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
Enteral Nutrition I: Orogastric and Nasogastric Feeding01:26

Enteral Nutrition I: Orogastric and Nasogastric Feeding

Enteral nutrition delivers nutrients directly to the stomach or small intestine through a tube. This method is appropriate for patients who cannot eat but still have a functioning digestive system. It is also beneficial for individuals with swallowing difficulties, anorexia, malabsorption, or those who have undergone gastrointestinal (GI) surgery.
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Efficacy and Safety of Risankizumab in Genital or Scalp Psoriasis in the UnlIMMited Phase 4 Randomized Clinical Trial at Week 16.

Dermatology and therapy·2025
Same author

Multiple Primary Acral Lentiginous Melanomas With BRCA1 Mutation.

JAAD case reports·2025
Same author

Autologous cell harvesting device provides repigmentation and improves quality-of-life for patients with stable vitiligo lesions in a large and diverse patient population.

Journal of the American Academy of Dermatology·2025
Same author

Management of androgenic alopecia: a systematic review of the literature.

Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology·2024
Same author

A phase 3 randomized trial of mavorixafor, a CXCR4 antagonist, for WHIM syndrome.

Blood·2024
Same author

Correction to: Dehydrated human amnion/chorion membrane allograft for postoperative wounds following Mohs micrographic surgery: a retrospective comparative evaluation.

Wounds : a compendium of clinical research and practice·2024
Same journal

Adult Cutaneous Chronic Graft-Versus-Host Disease: An In-Depth Review.

Journal of cutaneous medicine and surgery·2026
Same journal

'Cockade' or 'Targetoid' Variant of Syphilis.

Journal of cutaneous medicine and surgery·2026
Same journal

Tinea Imbricata.

Journal of cutaneous medicine and surgery·2026
Same journal

Intergenerational Clouston Syndrome.

Journal of cutaneous medicine and surgery·2026
Same journal

Herpes Zoster Ophthalmicus-Associated Trigeminal Trophic Syndrome.

Journal of cutaneous medicine and surgery·2026
Same journal

Borderline Lepromatous Leprosy Presenting Solely as a Nasal Plaque.

Journal of cutaneous medicine and surgery·2026
See all related articles

Related Experiment Video

Updated: Jun 20, 2026

Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology
07:26

Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology

Published on: August 22, 2022

Gnatophyma and otophyma.

Navid Ezra1, Joseph F Greco, Jennifer C Haley

  • 1Division of Dermatology, Department of Medicine, David Geffen Schoool of Medicine at UCLA, Los Angeles, CA, USA.

Journal of Cutaneous Medicine and Surgery
|September 23, 2009
PubMed
Summary
This summary is machine-generated.

This report details two rare cases of facial swelling disorders, gnatophyma (chin) and otophyma (ears), which are end-stage rosacea complications. Surgical management is recommended for these disfiguring phyma conditions.

More Related Videos

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
07:00

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas

Published on: February 28, 2019

Related Experiment Videos

Last Updated: Jun 20, 2026

Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology
07:26

Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology

Published on: August 22, 2022

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
07:00

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas

Published on: February 28, 2019

Area of Science:

  • Dermatology
  • Plastic Surgery

Background:

  • Phymas are progressive, disfiguring disorders of the face and ears, representing the final stage of rosacea.
  • While rhinophyma (nose) is most common, other forms include gnatophyma (chin), metophyma (forehead), otophyma (ears), and blepharophyma (eyelids).

Observation:

  • This case report presents two uncommon phyma presentations: gnatophyma and otophyma.
  • A 56-year-old man had chin growths, and a 73-year-old man presented with bilateral earlobe growths.

Findings:

  • Skin biopsies revealed characteristic changes including cystic follicular dilatation, keratin plugging, dermal scarring, and chronic inflammation.
  • Histopathological findings support the diagnosis of these rare phyma subtypes.

Implications:

  • Gnatophyma and otophyma are rare but significant manifestations of advanced rosacea.
  • Surgical intervention, proven effective for rhinophyma, is increasingly considered a primary treatment for all phymas.