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Updated: Jun 20, 2026

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Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
[Obstructive sleep apnoea and cardiovascular disease--a retrospective study]
Marta Drummond1, J C Winck, S Pereira
1Serviço de Pneumologia do Hospital de São João.
Revista Portuguesa De Pneumologia
|September 24, 2009
Summary
Obstructive Sleep Apnea (OSA) is common in patients with Cardiovascular Disease (CVD). This study found over half of OSA patients had CVD, with higher OSA severity in women with Arterial Hypertension.
Area of Science:
- Cardiology
- Sleep Medicine
- Public Health
Context:
- Obstructive Sleep Apnea (OSA) is increasingly recognized for its detrimental effects on cardiovascular physiology.
- Existing research suggests a link between OSA and the development of Cardiovascular Disease (CVD).
Purpose:
- To determine the prevalence of CVD in patients diagnosed with OSA.
- To assess the association between OSA severity and the presence of CVD.
- To investigate specific CVD subtypes within the OSA patient cohort.
Summary:
- A retrospective study analyzed 155 OSA patients, revealing a high prevalence of CVD (52.3%), with Arterial Hypertension being the most common condition (45.8%).
- Severe OSA was prevalent (52.9%), and significant associations were found between OSA severity and specific conditions, notably higher severity in women with Arterial Hypertension.
- Obesity (67.1%), Lipid Disorders (31%), and Diabetes Mellitus (11%) were also common comorbidities.
Impact:
- Highlights the significant burden of CVD in patients with OSA, underscoring the need for integrated screening and management.
- Provides evidence supporting further research into the pathophysiological mechanisms linking OSA and CVD.
- Informs clinical practice regarding the cardiovascular risks associated with OSA and its varying severity.
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